Survival in People Living with HIV with or without Recurrence of Hepatocellular Carcinoma after Invasive Therapy.

ABSTRACT:

Background and aims

To address the overall survival (OS) and recurrence (RE) in people living with HIV (PLWH) treated with invasive therapy (IT) for hepatocellular carcinoma (HCC).

Methods

This is a retrospective cohort study on 41 PLWH with HCC receiving IT, defined as liver resection (LR), orthotopic liver transplantation (OLT), radiofrequency thermo-ablation (RFTA) trans arterial chemo, or radioembolization (CRE). OS and RE were investigated by Kaplan-Meier curves. The Cox proportional hazard regression model was used for multivariate analyses.

Results

Recurrence occurred in 46.3% PLWH; in 36.7% of participants at 2 years and in 52% at 5 years from HCC diagnosis; it was less frequent in males, p = 0.036. Overall, 2- and 5-year survival after HCC diagnosis wa

SUBMITTER: Bertoni C 

PROVIDER: S-EPMC10046370 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature