Inflammation, Infiltration, and Evasion-Tumor Promotion in the Aging Breast.

ABSTRACT: Breast cancer is a significant cause of morbidity and mortality in women, with over two million new cases reported worldwide each year, the majority of which occur in post-menopausal women. Despite advances in early detection and treatment, approximately one-third of patients diagnosed with breast cancer will develop metastatic disease. The pathogenesis and progression of breast cancer are influenced by a variety of biological and social risk factors, including age, ethnicity, pregnancy status, diet, and genomic alterations. Recent advancements in breast cancer research have focused on harnessing the power of the patient's adaptive and innate immune systems for diagnostic and therapeutic purposes. The breast immune microenvironment plays a critical role in regulating tissue homeostasis and

SUBMITTER: Cruz-Reyes N 

PROVIDER: S-EPMC10046531 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature