Prefrontal Cortex Hemodynamics and Functional Connectivity Changes during Performance Working Memory Tasks in Older Adults with Sleep Disorders.

ABSTRACT:

Objective

Older adults with sleep disorders (SDs) show impaired working memory abilities, and working memory processes are closely related to the prefrontal cortex (PFC). However, the neural mechanism of working memory impairment in older adults with SD remains unclear. This study aimed to investigate changes in PFC function among older adults with SD when carrying out the N-back task by functional near-infrared spectroscopy (fNIRS).

Method

A total of 37 older adults with SDs were enrolled in this study and matched with 37 healthy older adults by gender, age, and years of education. Changes in PFC function were observed by fNIRS when carrying out the N-back task.

Results

The accuracy on the 0-back and 2-back tasks in the SD group was significantly lower than that in t

SUBMITTER: Gao J 

PROVIDER: S-EPMC10046575 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature