Photoelectrochemical Determination of Cardiac Troponin I as a Biomarker of Myocardial Infarction Using a Bi₂S₃ Film Electrodeposited on a BiVO₄-Coated Fluorine-Doped Tin Oxide Electrode.

ABSTRACT: A sensitive and selective label-free photoelectrochemical (PEC) immunosensor was designed for the detection of cardiac troponin I (cTnI). The platform was based on a fluorine-doped tin oxide (FTO)-coated glass photoelectrode modified with bismuth vanadate (BiVO₄) and sensitized by an electrodeposited bismuth sulfide (Bi₂S₃) film. The PEC response of the Bi₂S₃/BiVO₄/FTO platform for the ascorbic acid (AA) donor molecule was approximately 1.6-fold higher than the response observed in the absence of Bi₂S₃. The cTnI antibodies (anti-cTnI) were immobilized on the Bi₂S₃/BiVO₄/FTO platform surface to produce the anti-cTnI/Bi₂S₃/BiVO₄/FTO immunos

SUBMITTER: Monteiro TO 

PROVIDER: S-EPMC10046628 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature