Motus Vita Est: Fruit Flies Need to Be More Active and Sleep Less to Adapt to Either a Longer or Harder Life.

ABSTRACT:

Background

Activity plays a very important role in keeping bodies strong and healthy, slowing senescence, and decreasing morbidity and mortality. Drosophila models of evolution under various selective pressures can be used to examine whether increased activity and decreased sleep duration are associated with the adaptation of this nonhuman species to longer or harder lives.

Methods

For several years, descendants of wild flies were reared in a laboratory without and with selection pressure. To maintain the "salt" and "starch" strains, flies from the wild population (called "control") were reared on two adverse food substrates. The "long-lived" strain was maintained through artificial selection for late reproduction. The 24 h patterns of locomotor activity and sleep in

SUBMITTER: Zakharenko LP 

PROVIDER: S-EPMC10047790 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature