Autophagy-Related MicroRNA: Tumor miR-125b and Thyroid Cancers.

ABSTRACT:

Background

Autophagy is a stress response mechanism that causes cellular components to degrade. Its defects were associated with multiple pathologies, including cancers. Thyroid cancer is known to be the most prevalent form of malignant neoplasm among endocrine tumors. The aim of the study was to seek and comprehensively explore the role of autophagy related genes and proteins play in thyroid cancers through bioinformatics analysis with their detection in the tissue samples.

Methods

Bioinformatics analysis was performed to investigate autophagy related proteins and genes involvement in thyroid cancer progression. The experimental verification was done in cancer samples of one hundred and three patients with thyroid pathology included in the study. The miR-125blevel was detec

SUBMITTER: Spirina LV 

PROVIDER: S-EPMC10048312 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature