Emerging Roles of Endocannabinoids as Key Lipid Mediators for a Successful Pregnancy.

ABSTRACT: In recent years, Cannabis use/misuse for treating pregnancy-related symptoms and other chronic conditions has increased among pregnant women, favored by decriminalization and/or legalization of its recreational uses in addition to its easy accessibility. However, there is evidence that prenatal Cannabis exposure might have adverse consequences on pregnancy progression and a deleterious impact on proper neurodevelopmental trajectories in the offspring. Maternal Cannabis use could interfere with the complex and finely controlled role performed by the endocannabinoid system in reproductive physiology, impairing multiple gestational processes from blastocyst implantation to parturition, with long-lasting intergenerational effects. In this review, we discuss current clinica

SUBMITTER: Rava A 

PROVIDER: S-EPMC10048990 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature