TRPM7-Mediated Ca²⁺ Regulates Mussel Settlement through the CaMKKβ-AMPK-SGF1 Pathway.

ABSTRACT: Many marine invertebrates have planktonic larval and benthic juvenile/adult stages. When the planktonic larvae are fully developed, they must find a favorable site to settle and metamorphose into benthic juveniles. This transition from a planktonic to a benthic mode of life is a complex behavioral process involving substrate searching and exploration. Although the mechanosensitive receptor in the tactile sensor has been implicated in sensing and responding to surfaces of the substrates, few have been unambiguously identified. Recently, we identified that the mechanosensitive transient receptor potential melastatin-subfamily member 7 (TRPM7) channel, highly expressed in the larval foot of the mussel Mytilospsis sallei, was involved in substrate exploration for settlement. Here, we sh

SUBMITTER: He J 

PROVIDER: S-EPMC10049526 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature