Oscillatory biomarkers of autism: evidence from the innate visual fear evoking paradigm.

ABSTRACT: Autism spectrum disorder (ASD) is a neurodevelopmental disorder with multiple associated deficits in both social and cognitive functioning. Diagnosing ASD usually relies on subjective clinical competencies, and research on objective criteria for diagnosing ASD in the early stage is still in its infancy. A recent animal study showed that the looming-evoked defensive response was impaired in mice with ASD, but whether the effect will be observed in human and contribute to finding a robust clinical neural biomarker remain unclear. Here, to investigate the looming-evoked defense response in humans, electroencephalogram responses toward looming and corresponding control stimuli (far and missing type) were recorded in children with ASD and typical developed (TD) children. Results revealed that a

SUBMITTER: Han C 

PROVIDER: S-EPMC10050250 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature