Retinopathy of prematurity and neurodevelopmental outcomes in preterm infants: A systematic review and meta-analysis.

ABSTRACT:

Background

Retinopathy of prematurity (ROP) and abnormal brain development share similar risk factors and mechanisms. There has been contrasting evidence on the association of ROP with adverse neurodevelopmental outcomes.

Objective

We analysed the association between ROP at levels of severity and treatment with all neurodevelopmental outcomes until adolescence.

Data source

We followed PRISMA guidelines and searched Medline and Embase between 1 August 1990 and 31 March 2022.

Study selection and participants

Randomised or quasi-randomised clinical trials and observational studies on preterm infants (<37 weeks) with ROP [type 1 or severe ROP, type 2 or milder ROP, laser or anti-vascular endothelial growth factor (VEGF) treated] were included.

Data extraction an

SUBMITTER: Diggikar S 

PROVIDER: S-EPMC10050340 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature