Original and introduced lineages co-driving the persistence of Brucella abortus circulating in West Africa.

ABSTRACT:

Introduction

Brucellosis, a serious public health issue affecting animals and humans, is neglected in West Africa (WA).

Methods

In the present study, bio-typing, multi-locus sequence typing (MLST), multiple-locus variable-number tandem repeat analysis (MLVA), and whole genome sequencing single-nucleotide polymorphism (WGS-SNP) analysis were used to characterize the Brucella abortus (B. abortus) strains from WA.

Results

All of the 309 strains analyzed in this study were extracted and downloaded from the international MLVA bank and were from 10 hosts (cattle, humans, ovine, buffalo, dromedaries, horse, sheep, zebu, dog, and cat) distributed in 17 countries in WA. Based on the bio-typing, three biovars, dominated by B. abortus bv.3, were observed and report

SUBMITTER: Liu Z 

PROVIDER: S-EPMC10050740 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature