Prevalence and Characteristics of Myopia in Adult Non-Human Primates in Southwest China.

ABSTRACT:

Purpose

To investigate the prevalence of myopia in a large cohort of adult cynomolgus monkeys (Macaca fascicularis) at Yunnan Province in southwest China and describe the characteristics of myopic rhesus macaque eyes.

Methods

A total of 219 cynomolgus monkeys 14.07 ± 2.72 years old (range, 8-21) were randomly recruited for this study. We performed fundus photography and measurements of cycloplegic refractive error (RE) and axial length (AL) on macaques.

Results

A total of 429 eyes of 219 macaques were examined. The median RE was -1.25 diopters (D), and the median AL was 18.69 mm. The prevalence of myopia was 62.47%, and one-third of the myopic eyes were highly myopic. The presence of fundus tessellations was higher in myopic eyes than non-myopic eyes (42.54% vs. 6.21%

SUBMITTER: Ma Y 

PROVIDER: S-EPMC10050901 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature