Adult and Larval Tracheal Systems Exhibit Different Molecular Architectures in Drosophila.

ABSTRACT: Knowing the molecular makeup of an organ system is required for its in-depth understanding. We analyzed the molecular repertoire of the adult tracheal system of the fruit fly Drosophila melanogaster using transcriptome studies to advance our knowledge of the adult insect tracheal system. Comparing this to the larval tracheal system revealed several major differences that likely influence organ function. During the transition from larval to adult tracheal system, a shift in the expression of genes responsible for the formation of cuticular structure occurs. This change in transcript composition manifests in the physical properties of cuticular structures of the adult trachea. Enhanced tonic activation of the immune system is observed in the adult trachea, which encompasses the increa

SUBMITTER: Bossen J 

PROVIDER: S-EPMC10052349 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature