Emergence of SARS-CoV-2 spike protein at the vaccination site.

ABSTRACT:

Background

The anti-coronavirus disease 2019 (COVID-19) vaccines are of paramount importance in the fight against the COVID-19 pandemic. Both viral vector- and nucleic acid-based vaccines are known to effectively induce protection against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus by generating high antibody titers and effective T-cell responses to the spike protein they encode. Although these vaccines are being applied worldwide and have been extensively investigated, the immunomorphological events at the vaccination site with respect to SARS-CoV-2 spike protein expression have not yet been described.

Methods

We had the opportunity to examine the deltoid muscles of three men who died shortly after vaccination for unrelated reasons. We examined th

SUBMITTER: Beck A 

PROVIDER: S-EPMC10052447 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature