Machine learning algorithm to construct cuproptosis- and immune-related prognosis prediction model for colon cancer.

ABSTRACT:

Background

Over the past few years, research into the pathogenesis of colon cancer has progressed rapidly, and cuproptosis is an emerging mode of cellular apoptosis. Exploring the relationship between colon cancer and cuproptosis benefits in identifying novel biomarkers and even improving the outcome of the disease.

Aim

To look at the prognostic relationship between colon cancer and the genes associated with cuproptosis and the immune system in patients. The main purpose was to assess whether reasonable induction of these biomarkers reduces mortality among patients with colon cancers.

Method

Data obtained from The Cancer Genome Atlas and Gene Expression Omnibus and the Genotype-Tissue Expression were used in differential analysis to explore differential expression gen

SUBMITTER: Huang YY 

PROVIDER: S-EPMC10052662 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature