Characterization of serum polyunsaturated fatty acid profile in patients with inflammatory bowel disease.

ABSTRACT:

Background

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the digestive tract. The aetiology and pathogenesis of IBD are complex, which may lead to metabolic disorders. As a kind of metabolite, polyunsaturated fatty acid (PUFA) is closely related to IBD.

Objectives

The aim of this study was to explore the correlation between the serum PUFAs and the pathogenesis of IBD.

Design

The study is a hospital-based case-control study.

Methods

The serum free PUFAs of all participants, including 104 patients with IBD and 101 normal controls, were detected by liquid chromatography-mass spectrometry (LC-MS).

Results

Compared with the normal control, the levels of C18:2, α-C18:3 (ALA), ɤ-C18:3, C20:4 (AA), C20:5 (EPA), ω-3 C22:5, ω-6 C22:5 and C2

SUBMITTER: Jiang J 

PROVIDER: S-EPMC10052691 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature