Association between opioid therapy trajectories and potential opioid-related adverse health events.

ABSTRACT:

Purpose

We identified associations between membership in seven group-based trajectories based on supply of filled opioid prescriptions and potential opioid-related adverse health events over a 720-day window.

Methods

We identified two veteran cohorts with chronic non-cancer pain who initiated treatment with long-term opioid therapy between 2008 and 2015, excluding those with prior substance use disorder (n = 373 941) or non-SUD, opioid-related adverse outcome (n = 405 631) diagnoses. Outcomes of interest included opioid use disorder, non-opioid drug use disorder, and alcohol use disorder for the first cohort; or accidents resulting in wounds or injuries, self-inflicted injuries, opioid-related accidents and overdoses, alcohol and non-opioid drug-related accidents and overdos

SUBMITTER: Hayes CJ 

PROVIDER: S-EPMC10052807 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature