Efficacy and safety of mucous fistula refeeding in preterm infants: an exploratory randomized controlled trial.

ABSTRACT:

Background

This study aimed to evaluate whether mucous fistula refeeding (MFR) is safe and beneficial for the growth and intestinal adaptation of preterm infants with enterostomies.

Methods

This exploratory randomized controlled trial enrolled infants born before 35 weeks' gestation with enterostomy. If the stomal output was ≥ 40 mL/kg/day, infants were assigned to the high-output MFR group and received MFR. If the stoma output was < 40 mL/kg/day, infants were randomized to the normal-output MFR group or the control group. Growth, serum citrulline levels, and bowel diameter in loopograms were compared. The safety of MFR was evaluated.

Results

Twenty infants were included. The growth rate increased considerably, and the colon diameter was significantly larger after MFR

SUBMITTER: Lee ES 

PROVIDER: S-EPMC10053085 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature