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The distribution characteristics of global blaOXA-carrying Klebsiella pneumoniae.


ABSTRACT:

Objective

To analyze the distribution of blaOXA among global Klebsiella pneumoniae and the characteristics of blaOXA-carrying K. pneumoniae.

Materials and methods

The genomes of global K. pneumoniae were downloaded from NCBI by Aspera software. After quality check, the distribution of blaOXA among the qualified genomes was investigated by annotation with the resistant determinant database. The phylogenetic tree was constructed for the blaOXA variants based on the single nucleotide polymorphism (SNP) to explore the evolutionary relationship between these variants. The MLST (multi-locus sequence type) website and blastn tools were utilized to determine the sequence types (STs) of these blaOXA-carrying strains. and sample resource, isolation country, date and host were extracte

SUBMITTER: Meng L 

PROVIDER: S-EPMC10053090 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature