Prevalence and prognosis of frailty in older patients with stage B heart failure with preserved ejection fraction.

ABSTRACT:

Aims

Frailty in older patients with stage B heart failure with preserved ejection fraction (HFpEF) has not been fully explored. We evaluated the prevalence and prognostic significance of frailty in older patients diagnosed with stage B HFpEF.

Methods

Our prospective cohort study included inpatients aged ≥65 years who were followed up for 3 years. Stage B HFpEF was defined as cardiac structural or functional abnormalities with a left ventricular ejection fraction (LVEF) ≥ 50% without signs or symptoms. Frailty was assessed using the Fried phenotype. The primary outcome was 3-year all-cause mortality or readmission.

Results

Overall, 520 older inpatients diagnosed with stage B HFpEF [mean ± standard deviation age: 75.5 ± 6.25 years, male: 222 (42.7%)] were included in th

SUBMITTER: Meng C 

PROVIDER: S-EPMC10053163 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature