Optimizing exercise testing-based risk stratification to predict poor prognosis after acute heart failure.

ABSTRACT:

Aims

The timely selection of severe heart failure (HF) patients for cardiac transplantation and advanced HF therapy is challenging. Peak oxygen consumption (VO₂ ) values obtained by the cardiopulmonary exercise testing are used to determine the transplant recipient list. This study reassessed the prognostic predictability of peak VO₂ and compared it with the Heart Failure Survival Score (HFSS) in the modern optimized guideline-directed medical therapy (GDMT) era.

Methods and results

We retrospectively selected 377 acute HF patients discharged from the hospital. The primary outcome was a composite of all-cause mortality, or urgent cardiac transplantation. We divided these patients into the more GDMT (two or more types of GDMT) and less GDMT groups (fewer

SUBMITTER: Chen SM 

PROVIDER: S-EPMC10053263 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature