Applicability of new proposed criteria for iron deficiency in Japanese patients with heart failure.

ABSTRACT:

Aims

Iron deficiency (ID) is a common co-morbidity in patients with heart failure (HF). A recent study showed that ID defined by the current guideline criteria was not associated with worse clinical outcomes, and new ID criteria was proposed in patients with HF. However, the external applicability of the new proposed criteria is unclear. We sought to investigate the applicability of the proposed ID criteria in Japanese patients with HF.

Methods and results

We prospectively examined 763 patients with chronic HF from a Japanese multicentre registry. The proposed ID criteria were transferrin saturation (TSAT) < 20% and serum iron ≤13 mmol/L and the guideline ID criteria were serum ferritin <100 ng/mL or, when ferritin was 100-299 ng/mL, TSAT <20%. Among all patients (456 male,

SUBMITTER: Tada A 

PROVIDER: S-EPMC10053267 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature