A translatome-transcriptome multi-omics gene regulatory network reveals the complicated functional landscape of maize.

ABSTRACT:

Background

Maize (Zea mays L.) is one of the most important crops worldwide. Although sophisticated maize gene regulatory networks (GRNs) have been constructed for functional genomics and phenotypic dissection, a multi-omics GRN connecting the translatome and transcriptome is lacking, hampering our understanding and exploration of the maize regulatome.

Results

We collect spatio-temporal translatome and transcriptome data and systematically explore the landscape of gene transcription and translation across 33 tissues or developmental stages of maize. Using this comprehensive transcriptome and translatome atlas, we construct a multi-omics GRN integrating mRNAs and translated mRNAs, demonstrating that translatome-related GRNs outperform GRNs solely using transcriptomic data and

SUBMITTER: Zhu W 

PROVIDER: S-EPMC10053466 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature