The Role of Dietary Antioxidants and Their Potential Mechanisms in Alzheimer's Disease Treatment.

ABSTRACT: Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with cognitive decline and characterized by amyloid-β plaques and neurofibrillary tau tangles. Although AD's exact pathophysiology remains unclear, oxidative stress is known to play a role in the neurodegenerative process. Since no curative treatment exists, antioxidants represent a potential treatment for AD due to their ability to modulate oxidative stress. Therefore, this review aims to examine the impact of antioxidant supplementation and its potential mechanisms on cognitive function. The review primarily discusses research articles published between 2012 and 2022 reporting the results of clinical trials involving antioxidant supplementation on cognitive function in individuals with AD. Antioxidant supplem

SUBMITTER: Knight E 

PROVIDER: S-EPMC10054164 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature