Advances in Radionuclides and Radiolabelled Peptides for Cancer Therapeutics.

ABSTRACT: Radiopharmaceutical therapy, which can detect and treat tumours simultaneously, was introduced more than 80 years ago, and it has changed medical strategies with respect to cancer. Many radioactive radionuclides have been developed, and functional, molecularly modified radiolabelled peptides have been used to produce biomolecules and therapeutics that are vastly utilised in the field of radio medicine. Since the 1990s, they have smoothly transitioned into clinical application, and as of today, a wide variety of radiolabelled radionuclide derivatives have been examined and evaluated in various studies. Advanced technologies, such as conjugation of functional peptides or incorporation of radionuclides into chelating ligands, have been developed for advanced radiopharmaceutical cancer therapy

SUBMITTER: Chakraborty K 

PROVIDER: S-EPMC10054444 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature