Novel Sulfonamide Derivatives Containing a Piperidine Moiety as New Bactericide Leads for Managing Plant Bacterial Diseases.

ABSTRACT: Plant bacterial diseases are an intractable problem due to the fact that phytopathogens have acquired strong resistances for traditional pesticides, resulting in restricting the quality and yield of agricultural products around the world. To develop new agrochemical alternatives, we prepared a novel series of sulfanilamide derivatives containing piperidine fragments and assessed their antibacterial potency. The bioassay results revealed that most molecules displayed excellent in vitro antibacterial potency towards Xanthomonas oryzae pv. oryzae (Xoo) and Xanthomonas axonopodis pv. citri (Xac). In particular, molecule C₄ exhibited outstanding inhibitory activity toward Xoo with EC₅₀ value of 2.02 µg mL^-1

SUBMITTER: Xie J 

PROVIDER: S-EPMC10054644 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature