QSAR Models for the Prediction of Dietary Biomagnification Factor in Fish.

ABSTRACT: Xenobiotics released in the environment can be taken up by aquatic and terrestrial organisms and can accumulate at higher concentrations through the trophic chain. Bioaccumulation is therefore one of the PBT properties that authorities require to assess for the evaluation of the risks that chemicals may pose to humans and the environment. The use of an integrated testing strategy (ITS) and the use of multiple sources of information are strongly encouraged by authorities in order to maximize the information available and reduce testing costs. Moreover, considering the increasing demand for development and the application of new approaches and alternatives to animal testing, the development of in silico cost-effective tools such as QSAR models becomes increasingly important. In this study, a

SUBMITTER: Bertato L 

PROVIDER: S-EPMC10054725 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature