Trait repetitive negative thinking in depression is associated with functional connectivity in negative thinking state rather than resting state.

ABSTRACT: Resting-state functional connectivity (RSFC) has been proposed as a potential indicator of repetitive negative thinking (RNT) in depression. However, identifying the specific functional process associated with RSFC alterations is challenging, and it remains unclear whether alterations in RSFC for depressed individuals are directly related to the RNT process or to individual characteristics distinct from the negative thinking process per se. To investigate the relationship between RSFC alterations and the RNT process in individuals with major depressive disorder (MDD), we compared RSFC with functional connectivity during an induced negative-thinking state (NTFC) in terms of their predictability of RNT traits and associated whole-brain connectivity patterns using connectome-based predictive

SUBMITTER: Misaki M 

PROVIDER: S-EPMC10055358 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature