Development and Characterization of Pullulan-Based Orodispersible Films of Iron.

ABSTRACT: Iron deficiency is the principal cause of nutritional anemia and it constitutes a major health problem, especially during pregnancy. Despite the availability of various non-invasive traditional oral dosage forms such as tablets, capsules, and liquid preparations of iron, they are hard to consume for special populations such as pregnant women, pediatric, and geriatric patients with dysphagia and vomiting tendency. The objective of the present study was to develop and characterize pullulan-based iron-loaded orodispersible films (i-ODFs). Microparticles of iron were formulated by a microencapsulation technique, to mask the bitter taste of iron, and ODFs were fabricated by a modified solvent casting method. Morphological characteristics of the microparticles were identified by optical microsco

SUBMITTER: Gupta MS 

PROVIDER: S-EPMC10056616 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature