Polymorphisms in <i>VDR</i>, <i>CYP27B1</i>, <i>CYP2R1</i>, <i>GC</i> and <i>CYP24A1</i> Genes as Biomarkers of Survival in Non-Small Cell Lung Cancer: A Systematic Review.

ABSTRACT: The objective of this systematic review was to provide a compilation of all the literature available on the association between single-nucleotide polymorphisms (SNPs) in the genes involved in the metabolic pathway of vitamin D and overall survival (OS) and progression-free survival (PFS) in patients with non-small cell lung cancer (NSCLC). This systematic review was conducted in accordance with the PRISMA guidelines. It included all the literature published up to 1 November 2022 and was carried out in four databases (Medline [PubMed], Scopus, Web of Science, and Embase), using the PICO strategy, with relevant keywords related to the objective. The quality of the studies included was evaluated with an assessment tool derived from the Strengthening the Reporting of Genetic Association Studie

SUBMITTER: Pineda-Lancheros LE 

PROVIDER: S-EPMC10057500 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature