Nine New Pregnane Glycosides from the Cultivated Medicinal Plant Marsdenia tenacissima.

ABSTRACT: The ethnobotanical plant Marsdenia tenacissima has been used for hundreds of years for Dai people in Yunnan Province, China. Previously, chemical investigations on this plant have revealed that pregnane glycosides were the main biological constituents. Nine new pregnane glycosides, marsdeosides A-I (1-9), were isolated from cultivated dried stems of the medicinal plant Marsdenia tenacissima in this study. The structures were analyzed by extensive spectroscopic analysis, including 1D, 2D NMR, HRESIMS, and IR spectroscopic analysis. The absolute configurations of the sugar moieties were identified by comparing the R_f values and specific optical rotations with those of the commercially available standard samples and the data reported in the litera

SUBMITTER: Meng QQ 

PROVIDER: S-EPMC10058037 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature