The role of lactate dehydrogenase in hospitalized patients, comparing those with pulmonary versus non-pulmonary infections: A nationwide study.

ABSTRACT:

Background

Lactic dehydrogenase reflects target organ damage, and is associated with mortality in patients with infectious diseases.

Objective

The purpose of this study was to examine associations of serum lactic dehydrogenase levels with mortality, target organ damage and length of hospital stay in adults with pulmonary and non-pulmonary infections.

Methods

This nationwide retrospective cohort study comprised patients admitted with infections, to medical and surgical departments in eight tertiary hospitals during 2001-2020. Patients with available serum lactic dehydrogenase levels on admission and one week after were included, and stratified by the source of their infection: pulmonary vs. non-pulmonary. Associations of lactic dehydrogenase levels with mortality and t

SUBMITTER: Frenkel A 

PROVIDER: S-EPMC10058092 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature