A simple, time- and cost-effective, high-throughput depletion strategy for deep plasma proteomics.

ABSTRACT: We introduce a cost-effective, robust high-throughput-compatible plasma depletion method enabling in-depth profiling of plasma that detects >1300 proteins per run with a throughput of 60 samples per day. The method has been fully validated by processing >3000 samples with no apparent batch effect at a cost for the depletion step of ~$2.5 per sample.

SUBMITTER: Viode A 

PROVIDER: S-EPMC10058233 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature