In Vitro Hepatic Models to Assess Herb-Drug Interactions: Approaches and Challenges.

ABSTRACT: A newfound appreciation for the benefits of herbal treatments has emerged in recent decades. However, herbal medication production still needs to establish standardized protocols that adhere to strict guidelines for quality assurance and risk minimization. Although the therapeutic effects of herbal medicines are extensive, the risk of herb-drug interactions remains a serious concern, limiting their use. Therefore, a robust, well-established liver model that can fully represent the liver tissue is required to study potential herb-drug interactions to ensure herbal medicines' safe and effective use. In light of this, this mini review investigates the existing in vitro liver models applicable to detecting herbal medicines' toxicity and other pharmacological targets. This article analyz

SUBMITTER: N H 

PROVIDER: S-EPMC10058280 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature