Heritable Risk and Protective Genetic Components of Glaucoma Medication Non-Adherence.

ABSTRACT: Glaucoma is the leading cause of irreversible blindness, affecting 76 million globally. It is characterized by irreversible damage to the optic nerve. Pharmacotherapy manages intraocular pressure (IOP) and slows disease progression. However, non-adherence to glaucoma medications remains problematic, with 41-71% of patients being non-adherent to their prescribed medication. Despite substantial investment in research, clinical effort, and patient education protocols, non-adherence remains high. Therefore, we aimed to determine if there is a substantive genetic component behind patients' glaucoma medication non-adherence. We assessed glaucoma medication non-adherence with prescription refill data from the Marshfield Clinic Healthcare System's pharmacy dispensing database. Two standard measure

SUBMITTER: Barr JL 

PROVIDER: S-EPMC10058353 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature