CT-Derived Body Composition Is a Predictor of Survival after Esophagectomy.

ABSTRACT:

Background

Body composition can be accurately quantified based on computed tomography (CT) and typically reflects an individual's overall health status. However, there is a dearth of research examining the relationship between body composition and survival following esophagectomy.

Methods

We created a cohort consisting of 183 patients who underwent esophagectomy for esophageal cancer without neoadjuvant therapy. The cohort included preoperative PET-CT scans, along with pathologic and clinical data, which were collected prospectively. Radiomic, tumor, PET, and body composition features were automatically extracted from the images. Cox regression models were utilized to identify variables associated with survival. Logistic regression and machine learning models were developed

SUBMITTER: Iyer K 

PROVIDER: S-EPMC10058526 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature