Virological and Genetic Characterization of the Unusual Avian Influenza H14Nx Viruses in the Northern Asia.

ABSTRACT: Wild aquatic birds are generally identified as a natural reservoir of avian influenza viruses (AIVs), where a high diversity of subtypes has been detected. Some AIV subtypes are considered to have relatively low prevalence in wild bird populations. Six-year AIV surveillance in Siberia revealed sporadic cases of the rarely identified H14-subtype AIV circulation. Complete genome sequencing of three H14 isolates were performed, and the analysis indicated interconnections between low pathogenic avian influenza (LPAI) viruses. We conducted hemagglutination inhibition and virus neutralization assays, estimated the susceptibility of isolates to neuraminidase inhibitors, and characterized receptor specificity. Our study revealed circulation of a new H14N9 subtype described for the first time. Howe

SUBMITTER: Dubovitskiy N 

PROVIDER: S-EPMC10058565 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature