Alphatoxin Nanopore Detection of Aflatoxin, Ochratoxin and Fumonisin in Aqueous Solution.

ABSTRACT: Mycotoxins are toxic and carcinogenic metabolites produced by groups of filamentous fungi that colonize food crops. Aflatoxin B₁ (AFB₁), ochratoxin A (OTA) and fumonisin B₁ (FB₁) are among the most relevant agricultural mycotoxins, as they can induce various toxic processes in humans and animals. To detect AFB₁, OTA and FB₁ in the most varied matrices, chromatographic and immunological methods are primarily used; however, these techniques are time-consuming and expensive. In this study, we demonstrate that unitary alphatoxin nanopore can be used to detect and differentiate these mycotoxins in aqueous solution. The presence of AFB₁, OTA or FB₁ inside the nanopore induces reversible blockage of the ionic

SUBMITTER: Silva AARD 

PROVIDER: S-EPMC10058818 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature