Systematic Selection Signature Analysis of Chinese Gamecocks Based on Genomic and Transcriptomic Data.

ABSTRACT: Selection pressures driven by natural causes or human interference are key factors causing genome variants and signatures of selection in specific regions of the genome. Gamecocks were bred for cockfighting, presenting pea-combs, larger body sizes, stronger limbs, and higher levels of aggression than other chickens. In this study, we aimed to explore the genomic differences between Chinese gamecocks and commercial, indigenous, foreign, and cultivated breeds by detecting the regions or sites under natural or artificial selection using genome-wide association studies (GWAS), genome-wide selective sweeps based on the genetic differentiation index (F_ST), and transcriptome analyses. Ten genes were identified using GWAS and F_ST: gga-mir-6608-1, SOX5<

SUBMITTER: Ren X 

PROVIDER: S-EPMC10059269 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature