Photonic Crystal Enhanced Fluorescence: A Review on Design Strategies and Applications.

ABSTRACT: Nanoscale fluorescence emitters are efficient for measuring biomolecular interactions, but their utility for applications requiring single-unit observations is constrained by the need for large numerical aperture objectives, fluorescence intermittency, and poor photon collection efficiency resulting from omnidirectional emission. Photonic crystal (PC) structures hold promise to address the aforementioned challenges in fluorescence enhancement. In this review, we provide a broad overview of PCs by explaining their structures, design strategies, fabrication techniques, and sensing principles. Furthermore, we discuss recent applications of PC-enhanced fluorescence-based biosensors incorporated with emerging technologies, including nucleic acids sensing, protein detection, and steroid monitori

SUBMITTER: Xiong Y 

PROVIDER: S-EPMC10059769 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature