The Blood Microbiome and Health: Current Evidence, Controversies, and Challenges.

ABSTRACT: Blood is conventionally thought to be sterile. However, emerging evidence on the blood microbiome has started to challenge this notion. Recent reports have revealed the presence of genetic materials of microbes or pathogens in the blood circulation, leading to the conceptualization of a blood microbiome that is vital for physical wellbeing. Dysbiosis of the blood microbial profile has been implicated in a wide range of health conditions. Our review aims to consolidate recent findings about the blood microbiome in human health and to highlight the existing controversies, prospects, and challenges around this topic. Current evidence does not seem to support the presence of a core healthy blood microbiome. Common microbial taxa have been identified in some diseases, for instance, Legionell

SUBMITTER: Cheng HS 

PROVIDER: S-EPMC10059777 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature