Human Milk Oligosaccharides Are Associated with Lactation Stage and Lewis Phenotype in a Chinese Population.

ABSTRACT:

Background

Human milk oligosaccharides (HMOs) are the third most abundant component of human milk. Various factors may affect the concentration of HMOs, such as the lactation period, Lewis blood type, and the maternal secretor gene status.

Objectives

The purpose of this study is to investigate factors associated with HMO concentrations in Chinese populations.

Methods

A sub-sample of 481 was randomly selected from a large cross-sectional study in China (n = 6481) conducted in eight provinces (Beijing, Heilongjiang, Shanghai, Yunnan, Gansu, Guangdong, Zhejiang, and Shandong) between 2011 and 2013. HMO concentrations were determined by a high-throughput UPLC-MRM method. Various factors were collected through face-to-face interviews. Anthropometric measurement was

SUBMITTER: Ren X 

PROVIDER: S-EPMC10059825 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature