Oculo-dento-digital dysplasia: a systematic analysis of published dental literature.

ABSTRACT:

Introduction

Oculo-dento-digital dysplasia (ODDD, OMIM# 164200) is a rare genetic disorder caused by mutation in Gap junction alpha gene that encodes connexin 43 (Cx43) protein. In this paper, the case of a 16-year-old boy is reported who presented with the complaint of toothache. Examination revealed unusual facial features, i.e., long narrow nose, hypertelorism, prominent epicanthal folds along with syndactyly and camptodactyly. We have also compiled available dental literature on ODDD that will help clinicians in early diagnosis and management of this condition.

Materials and methods

A literature search was performed in PubMed NLM, EBSCO Dentistry & Oral Sciences Source, and EBSCO CINAHL Plus.

Results

A total of 309 articles were identified in the literature search

SUBMITTER: Hindu KD 

PROVIDER: S-EPMC10060216 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature