Relationship of insight to neurocognitive function and risk of recurrence in depression: A naturalistic follow-up study.

ABSTRACT:

Introduction

Major depressive disorder (MDD) is a highly recurrent mental illness accompanied by impairment of neurocognitive function. Lack of insight may affect patients' motivation to seek treatment, resulting in poor clinical outcomes. This study explores the relationship of insight to neurocognitive function and the risk of recurrence of depressive episodes in patients with MDD.

Methods

Demographic, clinical variables, and neurocognitive function measured with Intra-Extra Dimensional Set Shift (IED) from the Cambridge Neuropsychological Test Automated Battery (CANTAB) were collected from 277 patients with MDD. Among them, 141 participants completed a follow-up visit within 1-5 years. Insight was measured using the 17-item Hamilton Depression Rating Scale (HAM-D). To exp

SUBMITTER: Wang M 

PROVIDER: S-EPMC10060510 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature