FindNonCoding: rapid and simple detection of non-coding RNAs in genomes.

ABSTRACT:

Summary

Non-coding RNAs are often neglected during genome annotation due to their difficulty of detection relative to protein coding genes. FindNonCoding takes a pattern mining approach to capture the essential sequence motifs and hairpin loops representing a non-coding RNA family and quickly identify matches in genomes. FindNonCoding was designed for ease of use and accurately finds non-coding RNAs with a low false discovery rate.

Availability and implementation

FindNonCoding is implemented within the DECIPHER package (v2.19.3) for R (v4.1) available from Bioconductor. Pre-trained models of common non-coding RNA families are included for bacteria, archaea and eukarya.

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: Wright ES 

PROVIDER: S-EPMC10060727 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature