Altered neuromagnetic activity in default mode network in childhood absence epilepsy.

ABSTRACT:

Purpose

The electrophysiological characterization of resting state oscillatory functional connectivity within the default mode network (DMN) during interictal periods in childhood absence epilepsy (CAE) remains unclear. Using magnetoencephalographic (MEG) recordings, this study investigated how the connectivity within the DMN was altered in CAE.

Methods

Using a cross-sectional design, we analyzed MEG data from 33 children newly diagnosed with CAE and 26 controls matched for age and sex. The spectral power and functional connectivity of the DMN were estimated using minimum norm estimation combined with the Welch technique and corrected amplitude envelope correlation.

Results

Default mode network showed stronger activation in the delta band during the ictal period, howe

SUBMITTER: Wang Y 

PROVIDER: S-EPMC10060817 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature