The association between blood pressure variability and perihematomal edema after spontaneous intracerebral hemorrhage.

ABSTRACT:

Background

Perihematomal edema (PHE) after spontaneous intracerebral hemorrhage (sICH) is associated with clinical deterioration, but the etiology of PHE development is only partly understood.

Aims

We aimed to investigate the association between systemic blood pressure (BP) variability (BPV) and formation of PHE.

Methods

From a multicenter prospective observational study, we selected patients with sICH who underwent 3T brain MRI within 21 days after sICH, and had at least 5 BP measurements available in the first week after sICH. Primary outcome was the association between coefficient of variation (CV) of systolic BP (SBP) and edema extension distance (EED) using multivariable linear regression, adjusting for age, sex, ICH volume and timing of the MRI. In addition, we

SUBMITTER: Sondag L 

PROVIDER: S-EPMC10060834 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature