The relationship between gut microbiota and neonatal pathologic jaundice: A pilot case-control study.

ABSTRACT:

Background and objective

Neonatal jaundice is a common clinical disease in neonates. Pathologic jaundice is more harmful to neonates. There are a few studies on the biomarkers of pathologic jaundice and the correlation between gut microbiota and clinical indices. Therefore, we aimed to reveal the characteristics of gut microbiota in pathologic jaundice, provide potential biomarkers for the diagnosis of pathologic jaundice, and find the correlation between gut microbiota and clinical indices.

Methods

Fourteen neonates with physiologic jaundice were recruited into a control group (Group A). Additionally, 14 neonates with pathologic jaundice were recruited into a case group (Group B). The microbial communities were analyzed using 16S rDNA sequencing. LEfSe and the differences i

SUBMITTER: You JJ 

PROVIDER: S-EPMC10060978 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature