Clinical utility of immature reticulocyte fraction for identifying early red blood cell regeneration in anemic dogs.

ABSTRACT:

Background

Evaluating regeneration is essential for the classification and differential diagnosis of anemia in dogs. Early detection of regeneration is challenging in anemic dogs.

Objectives

This study assessed the value of immature reticulocyte fraction (IRF) in differentiating preregenerative anemia (PRA) from nonregenerative anemia (NRA) in dogs.

Animals

Ninety-four dogs: 49 controls and 45 with anemia.

Methods

Case-control study. Fractions of low-, medium- (MFR), and high-fluorescence reticulocytes (HFR), were measured using the ADVIA 2120i hematology analyzer. The IRF was calculated as the sum of percentages of MFR and HFR. Data from dogs with regenerative anemia (RA, n = 19), PRA (n = 11), and NRA (n = 15) were retrospectively analyzed. The value of IRF w

SUBMITTER: Jung JH 

PROVIDER: S-EPMC10061165 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature