Clinical utility of an immunoglobulin A-based serological panel for the diagnosis of chronic enteropathy in dogs.

ABSTRACT:

Background

A panel of IgA-based serologic assays might aid in the diagnosis of chronic enteropathy (CE) in dogs, a syndrome encompassing conditions such as food-responsive enteropathy, immunosuppressant-responsive enteropathy, and inflammatory bowel disease (also referred to as chronic inflammatory enteropathy). However, it is unclear whether these biomarkers discriminate between CE and other types of primary intestinal disorders.

Objectives

To evaluate a diagnostic panel that measures serum concentrations of IgA directed against OmpC (ACA), canine calprotectin (ACNA), and gliadin-derived peptides (AGA) in dogs with well-characterized intestinal diseases.

Animals

Fifty-five dogs with primary intestinal disease.

Methods

Serum ACA, ACNA, and AGA concentrations we

SUBMITTER: Langlois DK 

PROVIDER: S-EPMC10061200 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature